Publications

    1. K.F. Johnson, X. Dong, Y. Tsai, A. Wu, S.G. Clark, A. Vallie, S. Huang, C.J. Childs, R.K. Zwick, I. Glass, K.D. Walton, O.D. Klein, J.R. Spence. Mapping mesenchymal diversity in the developing human intestine and organoids. Nature Cell Biology (2026). DOI: 10.1038/s41556-026-02027-2 
    2. R.K. Zwick, M. Sharpley, J. Rispal, S. Rabizadeh, D. Boffelli, O.D. Klein. Regional organization of nutrient absorption across the small intestine. Nature Reviews Gastroenterology & Hepatology (2026). DOI: 10.1038/s41575-026-01225-5
      • Featured on the cover of its publication in October 2026!
    3. M.F. Griffin, J. Cook, A. Morgan, D. Boffelli, M. Downer, A.F. Spielman, N.J. Guardino, J.L. Guo, J.B.L. Parker, M. Januszyk, C. Valencia, M. Kunhert, J. Lu, R. Zwick, D.C. Wan, O.D. Klein, M.T. Longaker. Growth arrest specific-6 and angiotoxin receptor-like signaling drive oral regenerative wound repair. Science Translational Medicine (2025). DOI: 10.1126/scitranslmed.adk2101
    4. I.V. Choi and R.K. Zwick. To play Paneth or Goblet: Shapeshifting secretory cells read the room. Cell Stem Cell (2025). DOI: 10.1016/j.stem.2025.05.006
    5. R.K. Zwick, P. Kasparek*, B. Palikuqi*, S. Viragova*, L. Weichselbaum*, C.S. McGinnis*, K.L. McKinley, A. Rathnayake, D. Vaka, V. Nguyen, C. Trentesaux, E. Reyes, A.R. Gupta, Z.J. Gartner, R.M. Locksley, J.M. Gardner, S. Itzkovitz, D. Boffelli, O.D. Klein. Epithelial zonation along the mouse and human small intestine defines five discrete metabolic domains. Nature Cell Biology (2024). DOI: 10.1038/s41556-023-01337-z
    6. E.A. Reyes, D. Castillo-Azofeifa, J. Rispal, T. Wald, R.K. Zwick, B. Palikuqi, A. Mujukian, S. Rabizadeh, A.R. Gupta, J.M. Gardner, D. Boffelli, Z.J. Gartner, O.D. Klein. Epithelial TNF controls cell differentiation and CFTR activitiy to maintain intestinal mucin homeostasis. The Journal of Clinical Investigation (2023). DOI: 10.1172/JCI163591
    7. C.J. Childs, E.M. Holloway, C.W. Sweet, Y.H. Tsai, A. Wu, A. Vallie, M.K. Eiken, M.M. Capeling, R.K. Zwick, B. Palikuqi, C. Trentesaux, J.H. Wu, O. Pellón-Cardenas, C.J. Zhang, I. Glass, C. Loebel, Q. Yu, J.G. Camp, J.Z. Sexton, O.D. Klein, M.P. Verzi, J.R. Spence. EPIREGULIN creates a developmental niche for spatially organized human intestinal enteroids. JCI Insight. (2023) Mar 22;8(6):e165566. DOI: 10.1172/jci.insight.165566
    8. Z. A. Sullivan, W. Khoury-Hanold, J. Lim, C. Smillie, M. Biton, B.S. Reis, R.K. Zwick, S.D. Pope, K. Israni-Winger, R. Parsa, N.H. Philip, S.Rashed, N. Palm, A. Wang, D. Mucida, A. Regev, R. Medzhitov. (2021). γδ T cells regulate the intestinal response to nutrient sensing. Science 371. DOI: 10.1126/science.aba8310
    9. K. Bahar Halpern, H. Massalha, R.K. Zwick, A.E. Moor, D. Castillo-Azofeifa, M. Rozenberg, L. Farack, A. Egozi, D.R. Miller, I. Averbukh, Y. Harnik, N. Weinberg-Corem, F.J. de Sauvage, I. Amit, O.D. Klein, M. Sloshkes-Carmel, S. Itzkovitz. Lgr5+ telocytes are a signaling source at the intestinal villus tip. Nature Communications (2020). DOI: 10.1038/s41467-020-15714-x
    10. R.K. Zwick, B. Ohlstein, O.D. Klein. Intestinal renewal across the animal kingdom: comparing stem cell activity in mouse and Drosophila. American Journal of Physiology – GIL (2019). DOI:  10.1152/ajpgi.00353.2018
    11. R.K. Zwick, M. Rudolph, B. Shook, B. Holtrup, E. Roth, V. Lei, A. Van Keymeulen, V. Sweewaldt, S. Kwei, J. Wysolmerski, M. Rodeheffer, and V. Horsley. Adipocyte hypertrophy and lipid dynamics underlie mammary gland remodeling after lactation.  Nature Communications (2018). DOI: 10.1038/s41467-018-05911-0
    12. B. Shook, R.R. Wasko, G.C. Rivera Gonzalez, E. Salazar-Gatzimas, F. López-Giráldez, B.C. Dash, A.R. Muñoz-Rojas, K.D. Aultman, R.K. Zwick, V. Lei, J.L. Arbiser, K. Miller-Jensen, D.A. Clark, H.C. Hsia, V. Horsley. Myofibroblast  proliferation  and  heterogeneity  is  supported  by  macrophages  during  skin  repair. Science (2018). DOI: 10.1126/science.aar2971
    13. R.K. Zwick*, C.F. Guerrero-Juarez*, V. Horsley#, M. Plikus#. Anatomical, physiological, and functional diversity of adipose tissue.  Cell Metabolism (2018).  DOI: 10.1016/j.cmet.2017.12.002.
    14. B. Shook, G. Rivera Gonzalez, S. Ebmeier, G. Grisotti, R.K. Zwick, and V. Horsley. The role of adipocytes in tissue regeneration and stem cell niches. Annual Review of Cell and Developmental Biology (2016). DOI: 10.1146/annurev-cellbio-111315-125426
    15. J. Goldstein, E. Roth, N. Roberts, R.K. Zwick, S. Lin, S. Fletcher, A. Tadeu, C. Wu, A. Beck, C. Zeiss, M. Suarez-Farinas, and V. Horsley.  Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.  Molecular Biology of the Cell (2015).   DOI: 10.1091/mbc.E15-05-0282
    16. A.E. Bernhard, C. Dwyer, A. Idrizi, G. Bender and R.K. Zwick.  Long-term impacts of disturbance on nitrogen-cycling bacteria in a New England salt marsh.  Frontiers in Microbiology (2015).  DOI: 10.3389/fmicb.2015.00046
    17. R. Shaykhiev, R. Wang, R.K. Zwick, N.R. Hackett, R. Leung, M.A.S. Moore, C.S. Sima, I. Chao, R.J. Downey, Y. Strulovici-Barel, J. Salit, and R.G. Crystal.  Airway basal cells of healthy smokers express an embryonic stem cell signature relevant to lung cancer. Stem Cells (2013). DOI:10.1002/stem.1459
    18. L. Didon, R.K. Zwick, I. Chao, M.S. Walters, R. Wang, N.R. Hackett, and R.G. Crystal.  RFX3 modulation of FOXJ1 regulation of cilia genes in the human airway epithelium. Respir. Res.(2013).  DOI:10.1186/1465-9921-14-70
    19. N.R. Hackett, R. Shaykhiev, M.S. Walters, R.Wang, R.K. Zwick, B. Ferris, B. Witover, J. Salit, and R.G. Crystal.  The human airway epithelial basal cell transcriptome. PLoS ONE (2011). DOI: 10.1371/journal.pone.0018378
     
    * and # indicate equal contribution.

    NYU Grossman school of Medicine logo

    Designed by Razvan Matei | © 2026 Zwick Lab